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Expression analysis of human Integrin alpha V on HEK293/Human Integrin alpha V beta 6 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Integrin alpha V beta 6 Stable Cell Line or negative control cell using anti-human Integrin alpha V antibody followed by staining with FITC anti-mouse IgG Antibody.
Expression analysis of human Integrin beta 6 on HEK293/Human Integrin alpha V beta 6 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Integrin alpha V beta 6 Stable Cell Line or negative control cell using anti-human Integrin beta 6 antibody followed by staining with PE anti-human IgG Fc Antibody.
Fibronectin fragment, premium grade (Cat. No. FIN-H5113) immobilized on CM5 Chip can bind Cynomolgus ITGAV&ITGB6 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT6-C52W9) with an affinity constant of 0.946 µM as determined in a SPR assay (Biacore 8K) (Routinely tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Bexotegrast | PLN-74809 | Phase 3 Clinical | Pliant Therapeutics Inc | Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Cholangitis, Sclerosing | Details |
| IDL-2965 | IDL-2965 | Phase 2 Clinical | Indalo Therapeutics Inc | Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis | Details |
| Nesvategrast | OTT-166(OcuTerra Therapeutics); SF-0166 | Phase 2 Clinical | Scifluor Life Sciences Inc, OcuTerra Therapeutics Inc | Diabetic macular oedema; Diabetic Retinopathy; Macular Degeneration | Details |
| 18F-αvβ6-Binding-Peptide | 18F-αvβ6-BP | Phase 1 Clinical | National Cancer Institute, National Institutes Of Health | Rectal Neoplasms; Colonic Neoplasms; Coronavirus Disease 2019 (COVID-19); Pancreatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Coronaviridae Infections; Lung Neoplasms; Metastatic breast cancer | Details |
| [18F]FP-R01-MG | [18F]FP-R01-MG; [18F]FP-R01-MG-F2 | Phase 1 Clinical | Pliant Therapeutics Inc, Stanford University, Chinese Academy Of Medical Science & Peking Union Medical College | Small Cell Lung Carcinoma; Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19); Pancreatic Neoplasms; Cholangitis, Sclerosing; Brain metastases; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| Ga-68-Trivehexin | RAD-301 | Phase 1 Clinical | Trimt GmbH | Pancreatic Neoplasms; Carcinoma, Pancreatic Ductal | Details |
| Bexotegrast | PLN-74809 | Phase 3 Clinical | Pliant Therapeutics Inc | Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Cholangitis, Sclerosing | Details |
| IDL-2965 | IDL-2965 | Phase 2 Clinical | Indalo Therapeutics Inc | Metabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis | Details |
| Nesvategrast | OTT-166(OcuTerra Therapeutics); SF-0166 | Phase 2 Clinical | Scifluor Life Sciences Inc, OcuTerra Therapeutics Inc | Diabetic macular oedema; Diabetic Retinopathy; Macular Degeneration | Details |
| 18F-αvβ6-Binding-Peptide | 18F-αvβ6-BP | Phase 1 Clinical | National Cancer Institute, National Institutes Of Health | Rectal Neoplasms; Colonic Neoplasms; Coronavirus Disease 2019 (COVID-19); Pancreatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Coronaviridae Infections; Lung Neoplasms; Metastatic breast cancer | Details |
| [18F]FP-R01-MG | [18F]FP-R01-MG; [18F]FP-R01-MG-F2 | Phase 1 Clinical | Pliant Therapeutics Inc, Stanford University, Chinese Academy Of Medical Science & Peking Union Medical College | Small Cell Lung Carcinoma; Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19); Pancreatic Neoplasms; Cholangitis, Sclerosing; Brain metastases; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| Ga-68-Trivehexin | RAD-301 | Phase 1 Clinical | Trimt GmbH | Pancreatic Neoplasms; Carcinoma, Pancreatic Ductal | Details |
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